HYAL1 antibody

Catalog No. ABIN7670632

This anti-HYAL1 antibody is a Rabbit Polyclonal antibody detecting HYAL1 in ELISA. Suitable for Human.

Quick Overview for HYAL1 antibody (ABIN7670632)

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL1 antibody is un-conjugated

Application: ELISA

Product Details anti-HYAL1 Antibody

Purpose: Hyaluronidase 1/HYAL1 Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Hyaluronidase 1/HYAL1 protein expressed by Mammalian

Isotype: IgG

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Alternative Name: Hyaluronidase 1/HYAL1

Background: Hyaluronic Lase,yaluronic acid (HA) is a glycosaminoglycan that is believed to have numerous important biologic functions,including modulation of cell proliferation,migration,and differentiation,as well as the regulation of extracellular water and protein homeostasis. It is also an integral structural component of cartilage and other tissues and acts as a lubricant in joints. Hyaluronidases are a family of enzymes that catalyse the degradation of HA. In humans,there are five functional hyaluronidases: HYAL1,HYAL2,HYAL3,HYAL4 and HYAL5 (also known as SPAM1 or PH-20), plus a pseudogene,HYAL6 (also known as HYALP1). HYAL-1 is present in many tissues and is predominantly found in the plasma and urine (PMID: 16600643). In addition to its function in normal cellular hyaluronan turnover,human HYAL-1 is implicated in cancer proliferation,angiogenesis,and inflammatory diseases

UniProt: Q12794

Pathways: Glycosaminoglycan Metabolic Process