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IL-18 antibody

The Rabbit Polyclonal anti-IL-18 antibody has been validated for ELISA. It is suitable to detect IL-18 in samples from Human.
Catalog No. ABIN7670661

Quick Overview for IL-18 antibody (ABIN7670661)

Target

See all IL-18 (IL18) Antibodies
IL-18 (IL18) (Interleukin 18 (IL18))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This IL-18 antibody is un-conjugated

Application

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ELISA
  • Purpose

    IL-18/IL-1F4 Polyclonal Antibody(Capture/Detector)

    Purification

    Antigen Affinity Purification

    Immunogen

    Recombinant Human IL-18/IL-1F4 protein expressed by E.coli

    Isotype

    IgG
  • Application Notes

    ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    Sterile PBS , pH 7.4

    Preservative

    Without preservative

    Handling Advice

    Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C Valid for 1 month or -20°C Valid for 12 months

    Expiry Date

    12 months
  • Target

    IL-18 (IL18) (Interleukin 18 (IL18))

    Alternative Name

    IL-18/IL-1F4

    Background

    IL18,IL-18, IGIF, IL1F4,Iboctadekin,Interferon gamma-inducing factor,InterLeukin-1 gamma (IL-1 gamma),Pro-inflammatory cytokine primarily involved in epithelial barrier repair,polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.Upon binding to Il18R1 and Il18RAP,forms a signaling ternary complex which activates NF-kappa-B,triggering synthesis of inflammatory mediators.Synergizes with Il12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

    UniProt

    Q14116

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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