E2F5 antibody (AA 101-200)
Quick Overview for E2F5 antibody (AA 101-200) (ABIN733673)
Target
See all E2F5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 101-200
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Purpose
- E2F5 Polyclonal Antibody
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Cross-Reactivity
- Human, Rat
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Predicted Reactivity
- Mouse,Dog,Cow,Pig,Horse,Chicken
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human E2F5
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Isotype
- IgG
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Application Notes
- WB(1:300-5000),
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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: "Analysis of genetic aberrations on chromosomal region 8q21-24 identifies E2F5 as an oncogene with copy number gain in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 1, pp. 465, (2013) (PubMed).
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- E2F5
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Alternative Name
- E2F5
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Background
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Synonyms: E2F-5, Transcription factor E2F5, E2F5
Background: Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
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Gene ID
- 1875
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UniProt
- Q15329
Target
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