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alpha Actinin 4 antibody

ACTN4 Reactivity: Human, Mouse, Rat WB, FACS, IHC (p), IF (cc) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN733778
  • Target See all alpha Actinin 4 (ACTN4) Antibodies
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Reactivity
    • 86
    • 43
    • 40
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 79
    • 7
    Rabbit
    Clonality
    • 66
    • 19
    Polyclonal
    Conjugate
    • 54
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This alpha Actinin 4 antibody is un-conjugated
    Application
    • 67
    • 30
    • 26
    • 18
    • 15
    • 14
    • 13
    • 11
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Actinin alpha 4
    Isotype
    IgG
    Top Product
    Discover our top product ACTN4 Primary Antibody
  • Application Notes
    WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Alternative Name
    alpha Actinin 4 (ACTN4 Products)
    Synonyms
    fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody
    Background

    Synonyms: Actinin alpha 4, alpha-Actinin 4, alpha Actinin-4, actinin 4, actinin4, actinin-4, ACTN 4, ACTN4, DKFZp686K23158, F actin cross linking protein, FSGS 1, FSGS, FSGS1, Non muscle alpha actinin 4.

    Background: Loading Control Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008].

    Gene ID
    81
    Pathways
    Proton Transport
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