Prothrombin antibody (AA 70-280)

Catalog No. ABIN7673035

This anti-Prothrombin antibody is a Rabbit Polyclonal antibody detecting Prothrombin in WB and ELISA. Suitable for Human.

Quick Overview for Prothrombin antibody (AA 70-280) (ABIN7673035)

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prothrombin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Prothrombin Antibody

Binding Specificity: AA 70-280

Purpose: F2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 70-280aa

Immunogen: coagulation factor II(thrombin)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Prothrombin

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Alternative Name: F2

Background:

Synonyms: Prothrombin|Coagulation factor II|Activation peptide fragment 1|Activation peptide fragment 2|Thrombin light chain|Thrombin heavy chain|F2

Background: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

Molecular Weight: 72 kDa

Gene ID: 2147

UniProt: P00734

Pathways: Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling