Fc epsilon RI/FCER1A antibody (FITC)

Catalog No. ABIN7673258

This Armenian Hamster Monoclonal antibody specifically detects Fc epsilon RI/FCER1A in FACS. It exhibits reactivity toward Mouse.

Quick Overview for Fc epsilon RI/FCER1A antibody (FITC) (ABIN7673258)

Target: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This Fc epsilon RI/FCER1A antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: MAR-1

Product Details anti-Fc epsilon RI/FCER1A Antibody (FITC)

Purpose: FITC Anti-Mouse FcεRIα Antibody

Purification: 0

Purity: 0

Isotype: IgG

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Fc epsilon RI/FCER1A

Target: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Alternative Name: FcepsilonRIalpha

Background:

Synonyms: Fc-epsilon RI-alpha|FcERI|Fcer1a|High affinity immunoglobulin epsilon receptor subunit alpha

Background: FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

Molecular Weight: 0

Gene ID: 14125

UniProt: P20489

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process