IL-5 antibody (PE)

Catalog No. ABIN7673674

This anti-IL-5 antibody is a Rat Monoclonal antibody detecting IL-5 in FACS. Suitable for Human and Mouse.

Quick Overview for IL-5 antibody (PE) (ABIN7673674)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-5 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: TRFK5

Product Details anti-IL-5 Antibody (PE)

Purpose: PE Anti-Human/Mouse IL-5 Antibody

Purification: 0

Purity: 0

Isotype: IgG1, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: IL-5

Background:

Synonyms: B-cell differentiation factor I|IL-5|Interleukin-5|T-cell replacing factor|TRF

Background: IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70 % identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

Molecular Weight: 0

Gene ID: 356716191

UniProt: P05113, P04401

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour