ITGA4 antibody (PerCP-Cy5.5)

Catalog No. ABIN7674330

The Rat Monoclonal anti-ITGA4 antibody has been validated for FACS. It is suitable to detect ITGA4 in samples from Mouse.

Quick Overview for ITGA4 antibody (PerCP-Cy5.5) (ABIN7674330)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is conjugated to PerCP-Cy5.5

Application: Flow Cytometry (FACS)

Clone: R1-2

Product Details anti-ITGA4 Antibody (PerCP-Cy5.5)

Purpose: PerCP-Cy5.5 Anti-Mouse CD49d Antibody

Purification: 0

Purity: 0

Isotype: IgG2b, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: CD49d

Background:

Synonyms: α4 integrin|VLA-4 α chain|integrin α4|ITGA4

Background: CD49d is a 150 kD glycoprotein, also known as α4 integrin or VLA-4 α chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two β chains, β1 (CD29) or β7, to form the VLA-4 (integrin α4β1) or LPAM-1 (integrin α4β7) complexes. CD49d plays a critical role in adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin.

Molecular Weight: 0

Gene ID: 16401

UniProt: Q00651

Pathways: Integrin Complex