PHF1 antibody (AA 1-250)

Catalog No. ABIN7674363

The Rabbit Polyclonal anti-PHF1 antibody is suitable to detect PHF1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for PHF1 antibody (AA 1-250) (ABIN7674363)

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PHF1 Antibody

Binding Specificity: AA 1-250

Purpose: PHF-1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-250aa

Immunogen: PHD finger protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PHF1

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Alternative Name: PHF-1

Background:

Synonyms: MTF2L2| PCL1| PHD finger protein 1| PHF1| PHF2| Polycomb like protein 1| Protein PHF1

Background: Plant homeodomain finger protein 1 (PHF1) has a specific role in histone modification and in non-homologous end joining. It is a human homolog of the Drosophila protein Polycomb-like protein. PHF1 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex: it is however unclear whether recruitment of the PRC2 complex to H3K36me3 leads to enhance or inhibit H3K27me3 methylation mediated by the PRC2 complex. PHF1 regulates also p53/TP53 stability.

Molecular Weight: 62-70 kDa

Gene ID: 5252

UniProt: O43189