ULK1 antibody (pSer556)

Catalog No. ABIN7674408

The Rabbit Monoclonal anti-ULK1 antibody is suitable to detect ULK1 in samples from Human. It has been validated for WB.

Quick Overview for ULK1 antibody (pSer556) (ABIN7674408)

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ULK1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 0

Product Details anti-ULK1 Antibody

Binding Specificity: pSer556

Purpose: Phospho-ULK1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: Peptide

Immunogen: peptide

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Alternative Name: ULK1ULK1

Background:

Synonyms: Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog (ATG1, hATG1)|Unc-51-like kinase 1|ULK1|KIAA0722

Background: ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).

Molecular Weight: 140-150 kDa

Gene ID: 8408

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagy