UNC5D antibody

Catalog No. ABIN7674586

This anti-UNC5D antibody is a Rabbit Polyclonal antibody detecting UNC5D in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for UNC5D antibody (ABIN7674586)

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5D antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-UNC5D Antibody

Purpose: UNC5D-Specific antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: unc-5 homolog D(C. elegans)

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for UNC5D

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Alternative Name: UNC5D

Background:

Synonyms: Netrin receptor UNC5D|Protein unc-5 homolog 4|Protein unc-5 homolog D|UNC5D|KIAA1777|UNC5H4

Background: UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5D.

Molecular Weight: 60 kDa

UniProt: Q6UXZ4