NCR1 antibody (FineTest®700)

Catalog No. ABIN7675486

The Rat Monoclonal anti-NCR1 antibody has been validated for FACS. It is suitable to detect NCR1 in samples from Mouse.

Quick Overview for NCR1 antibody (FineTest®700) (ABIN7675486)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This NCR1 antibody is conjugated to FineTest®700

Application: Flow Cytometry (FACS)

Clone: 29A1-4

Product Details anti-NCR1 Antibody (FineTest®700)

Purpose: FineTest®700 Anti-Mouse CD335/NKp46 Antibody

Isotype: IgG2a, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: CD335

Background:

Synonyms: Ly94|Lymphocyte antigen 94|NK-p46|mAR-1|mNKp46

Background: CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells, it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

Molecular Weight: 0

Gene ID: 17086

UniProt: Q8C567

Pathways: Regulation of Leukocyte Mediated Immunity