GDF1 antibody (AA 301-372) (HRP)

Catalog No. ABIN734537

The Rabbit Polyclonal anti-GDF1 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect GDF1 in samples from Human.

Quick Overview for GDF1 antibody (AA 301-372) (HRP) (ABIN734537)

Target: GDF1 (Growth Differentiation Factor 1 (GDF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GDF1 Antibody (HRP)

Binding Specificity: AA 301-372

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDF-1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GDF1

Target: GDF1 (Growth Differentiation Factor 1 (GDF1))

Alternative Name: GDF1

Background:

Synonyms: DORV, DTGA3, Embryonic growth/dferentiation factor 1, GDF 1, GDF-1, GDF1, GDF1_HUMAN, Growth dferentiation factor 1.

Background: This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a monocistronic mRNA early in development, and from a bicistronic mRNA in later stages that also encodes the LAG1 homolog, ceramide synthase 1 gene.