IL16 antibody (AA 25-125)

Catalog No. ABIN735068

The Rabbit Polyclonal anti-IL16 antibody has been validated for WB, ELISA, IHC (p), IHC (fro), IF (p) and IF (cc). It is suitable to detect IL16 in samples from Mouse.

Quick Overview for IL16 antibody (AA 25-125) (ABIN735068)

Target: IL16 (Interleukin 16 (IL16))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-IL16 Antibody

Binding Specificity: AA 25-125

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-16

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IL16

Target: IL16 (Interleukin 16 (IL16))

Alternative Name: IL-16

Background:

Synonyms: Interleukin-16, HGNC:5980, HsT19289, Interleukin 16 precursor, LCF, Lymphocyte Chemotactic Factor, IL16, Lymphocyte chemoattractant factor, PrIL16, IL16_HUMAN.

Background: IL16 is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.

Gene ID: 3603