P4HTM antibody (AA 201-300) (Cy3)

Catalog No. ABIN735671

The Rabbit Polyclonal anti-P4HTM antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect P4HTM in samples from Mouse and Rat.

Quick Overview for P4HTM antibody (AA 201-300) (Cy3) (ABIN735671)

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HTM antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-P4HTM Antibody (Cy3)

Binding Specificity: AA 201-300

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PH-4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for P4HTM

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Alternative Name: P4htm

Background:

Synonyms: Transmembrane prolyl 4-hydroxylase, Proline hydrolase 4, proline 4-hydroxylase, P4htm, hypoxia-inducible factor prolyl 4-hydroxylase, P4H-TM, H-prolyl hydroxylase PH-4, P4HTM_HUMAN, Hypoxia-inducible factor prolyl hydroxylase 4, H-PH4, H-prolyl hydroxylase 4, HPH-4, transmembrane prolyl 4-hydroxylase isoform a, P4HTM, EGLN4, HPH4, P4H-TM, PH-4, PH4, PHD4, P4H with transmembrane domain, Prolyl hydroxlase domain-containing 4, hypoxia inducible factor prolyl 4 hydroxylase, H-prolyl hydroxylase 4.

Background: The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].