Peroxiredoxin 3 antibody (AA 161-256) (HRP)

Catalog No. ABIN735722

The Rabbit Polyclonal anti-Peroxiredoxin 3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect Peroxiredoxin 3 in samples from Human and Rat.

Quick Overview for Peroxiredoxin 3 antibody (AA 161-256) (HRP) (ABIN735722)

Target: Peroxiredoxin 3 (PRDX3)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Peroxiredoxin 3 Antibody (HRP)

Binding Specificity: AA 161-256

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PRDX3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Peroxiredoxin 3

Target: Peroxiredoxin 3 (PRDX3)

Alternative Name: PRDX3/peroxiredoxin 3

Background:

Synonyms: AOP1, MER5, AOP-1, SP-22, HBC189, PRO1748, prx-III, Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, Peroxiredoxin III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3

Background: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

Gene ID: 10935

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process