Peroxiredoxin 3 antibody (AA 239-256)

Catalog No. ABIN3032188

This Rabbit Polyclonal antibody specifically detects Peroxiredoxin 3 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Peroxiredoxin 3 antibody (AA 239-256) (ABIN3032188)

Target: Peroxiredoxin 3 (PRDX3)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Peroxiredoxin 3 Antibody

Binding Specificity: AA 239-256

Purpose: Peroxiredoxin 3 Antibody / PRDX3

Purification: Antigen affinity

Immunogen: Amino acids 239-256 (TIKPSPAASKEYFQKVNQ-human) were used as the immunogen for this Peroxiredoxin 3 antibody.

Isotype: IgG

Application Details

Application Notes: Titration of the Peroxiredoxin 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: The lyophilized Peroxiredoxin 3 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Peroxiredoxin 3

Target: Peroxiredoxin 3 (PRDX3)

Alternative Name: Peroxiredoxin 3

Background: Peroxiredoxin 3 is a mitochondrial protein belonging to the AhpC/TSA family. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that Peroxiredoxin 3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells.

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process