GRM4/6 antibody (AA 301-400)

Catalog No. ABIN735998

Product Details anti-GRM4/6 Antibody

Target: GRM4/6 (Glutamate Receptor, Metabotropic 4/6 (GRM4/6))

Binding Specificity: AA 301-400

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRM4/6 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects Metabotropic Glutamate Receptor 4. It may also detect Metabotropic Glutamate Receptor 6 due to sequence similarity.

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GRM4/6

Target: GRM4/6 (Glutamate Receptor, Metabotropic 4/6 (GRM4/6))

Abstract: GRM4/6 Products

Background:

Synonyms: mGlu4, GPRC1D, MGLUR4, Metabotropic glutamate receptor 4, GRM4

Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Gene ID: 2914

UniProt: Q14833