GRM4/6 antibody (AA 301-400) (HRP)

Catalog No. ABIN736007

The Rabbit Polyclonal anti-GRM4/6 antibody is suitable to detect GRM4/6 in samples from Mouse and Rat. It has been validated for ELISA, IHC (fro) and IHC (p).

Quick Overview for GRM4/6 antibody (AA 301-400) (HRP) (ABIN736007)

Target: GRM4/6 (Glutamate Receptor, Metabotropic 4/6 (GRM4/6))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRM4/6 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GRM4/6 Antibody (HRP)

Binding Specificity: AA 301-400

Specificity: This antibody detects Metabotropic Glutamate Receptor 4. It may also detect Metabotropic Glutamate Receptor 6 due to sequence similarity.

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 4

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GRM4/6

Target: GRM4/6 (Glutamate Receptor, Metabotropic 4/6 (GRM4/6))

Background:

Synonyms: mGlu4, GPRC1D, MGLUR4, Metabotropic glutamate receptor 4, GRM4

Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Gene ID: 2914

UniProt: Q14833