HMGA1 antibody (AA 51-107)

Catalog No. ABIN736626

This anti-HMGA1 antibody is a Rabbit Polyclonal antibody detecting HMGA1 in WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). Suitable for Human and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for HMGA1 antibody (AA 51-107) (ABIN736626)

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HMGA1 Antibody

Binding Specificity: AA 51-107

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HMGA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-HMGA1 antibody (ABIN736626)

Uchikura, Matsubara, Muto, Matsubara, Fujioka, Matsumoto, Sugiyama: "Extranuclear Translocation of High-Mobility Group A1 Reduces the Invasion of Extravillous Trophoblasts Involved in the Pathogenesis of Preeclampsia." in: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697250, (2017) (PubMed).

Target Details for HMGA1

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Alternative Name: HMGA1

Background:

Synonyms: HMG-R, HMGIY, HMGA1A, High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein A1, High mobility group protein R, HMGA1

Background: HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.

Gene ID: 3159

UniProt: P17096

Pathways: Nuclear Hormone Receptor Binding, Autophagy