HMGA1 antibody (AA 64-93)
Quick Overview for HMGA1 antibody (AA 64-93) (ABIN3031200)
Target
See all HMGA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 64-93
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Purpose
- HMGA1 Antibody
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat, Hamster
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Purification
- Purified
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Immunogen
- A portion of amino acids 64-93 from the human protein was used as the immunogen for this HMGA1 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the HMGA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the HMGA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
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Alternative Name
- HMGA1
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Background
- HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.
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UniProt
- P17096
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Pathways
- Nuclear Hormone Receptor Binding, Autophagy
Target
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