HMGA1 antibody (AA 64-93)

Catalog No. ABIN3031200

Product Details anti-HMGA1 Antibody

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Binding Specificity: AA 64-93

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Hamster

Purification: Purified

Immunogen: A portion of amino acids 64-93 from the human protein was used as the immunogen for this HMGA1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the HMGA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HMGA1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for HMGA1

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Alternative Name: HMGA1 (HMGA1 Products)

Synonyms: HMG-R antibody, HMGA1A antibody, HMGIY antibody, Hmgi antibody, Hmgiy antibody, hmga1 antibody, hmgiy antibody, wu:fb12b06 antibody, wu:fb18f11 antibody, wu:fc19f01 antibody, wu:fi38b05 antibody, zgc:85677 antibody, AL023995 antibody, Hmga1a antibody, Hmga1b antibody, Hmgy antibody, HMG-I(Y) antibody, HMG-Y antibody, HMGA1 antibody, zgc:153948 antibody, high mobility group AT-hook 1 antibody, high mobility group protein HMG-I/HMG-Y antibody, high mobility group AT-hook 1a antibody, high mobility group AT-hook 1b antibody, HMGA1 antibody, Hmga1 antibody, TSC_c24220 antibody, hmga1a antibody, LOC705105 antibody, hmga1b antibody

Background: HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.

UniProt: P17096

Pathways: Nuclear Hormone Receptor Binding, Autophagy