HMGA1 antibody (C-Term)
Quick Overview for HMGA1 antibody (C-Term) (ABIN952761)
Target
See all HMGA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 71-101, C-Term
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Specificity
- This antibody recognizes Human and Mouse HMGA1 / HMGIY (C-term).
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Purification
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogen
- KLH conjugated synthetic peptide between 71~101 amino acids from the C-terminal region of Human HMGA1 / HMGIY
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
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Alternative Name
- HMGA1 / HMGIY
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Background
- HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.Synonyms: High mobility group AT-hook protein 1, High mobility group protein A1, High mobility group protein HMG-I/HMG-Y, High mobility group protein R
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Molecular Weight
- 11676 Da
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Gene ID
- 3159
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NCBI Accession
- NP_002122
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Pathways
- Nuclear Hormone Receptor Binding, Autophagy
Target
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