WNV NS1 antibody
Quick Overview for WNV NS1 antibody (ABIN7794862)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-West Nile Virus, NS1 (Clone WNV-3562)
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Specificity
- Anti-West Nile virus (Clone WNV-3562) is specific for WNV non-structural protein 1 (NS1). There is no cross-reactivity with other Flavivirus. Background West Nile Virus (WNV) is a mosquito-borne, enveloped, positive-stranded RNA flavivirus1. Flavivirus nonstructural protein NS1 has been proposed as an antibody target to avoid antibody-dependent enhancement2. NS1 is a 46-55 kDa glycoprotein that is expressed as a dimer on the cell surface and as a soluble hexamer in the extracellular space and in circulation during infection. WNV NS1 dimer consists of a AY-roll, wing, and AY-ladder.
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Purification
- This monoclonal antibody is purified by ion exchange chromatography.
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Isotype
- IgG1 kappa
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Restrictions
- For Research Use only
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Concentration
- 1 μg/mL
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Buffer
- Formulated in 0.015 M phosphate buffered saline (0.85 % NaCl), pH 7.2 and contains 0.05 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- This purified antibody is stable when stored at 2-8°C. Do not freeze.
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- WNV NS1 (West Nile Virus NS1 (WNV NS1))
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Alternative Name
- West Nile Virus, NS1
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Target Type
- Viral Protein
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Background
- NS1, Non-structural protein 1, WNV,
Target
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