WNV Core antibody (N-Term)

Catalog No. ABIN7794903

The Rabbit Polyclonal anti-WNV Core antibody is suitable to detect WNV Core in samples from West Nile Virus (WNV).

Quick Overview for WNV Core antibody (N-Term) (ABIN7794903)

Target: WNV Core (West Nile Virus Genome polyprotein (WNV Core))

Reactivity: West Nile Virus (WNV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNV Core antibody is un-conjugated

Application: Please inquire

Product Details anti-WNV Core Antibody

Binding Specificity: N-Term

Purpose: Anti-West Nile Virus Core (NT) (WNV Core)

Specificity: Rabbit Anti-West Nile Virus Core (WNV Core) recognizes an epitope near the N-terminus of WNV Core. This polyclonal antibody was purified using affinity chromatography. Background West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state (reviewed in 1). Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins1 which play a major role for WNV entry into target cells.2,3 The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.4

Application Details

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/mL

Buffer: This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02 % sodium azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Target Details for WNV Core

Target: WNV Core (West Nile Virus Genome polyprotein (WNV Core))

Alternative Name: West Nile Virus Core

Target Type: Viral Protein