WNV E antibody (Internal Region)

Catalog No. ABIN7794904

The Rabbit Polyclonal anti-WNV E antibody (ABIN7794904) specifically detects WNV E. The antibody is reactive with West Nile Virus (WNV) samples.

Quick Overview for WNV E antibody (Internal Region) (ABIN7794904)

Target: WNV E (West Nile Virus Envelope (WNV E))

Reactivity: West Nile Virus (WNV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNV E antibody is un-conjugated

Application: Please inquire

Product Details anti-WNV E Antibody

Binding Specificity: Internal Region

Purpose: Anti-West Nile Virus Envelope Protein (Intermediate Domain) (WNV Env)

Specificity: Rabbit Anti-West Nile Virus Envelope Protein (WNV Env) recognizes an epitope in the intermediate domain of WNV Env. This polyclonal antibody was purified using affinity chromatography. Background West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state (reviewed in 1). Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins.1 While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway,2 the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein.3 The WNV receptor has recently been identified as alpha v beta 3 integrin.4

Application Details

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/mL

Buffer: This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02 % sodium azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Target Details for WNV E

Target: WNV E (West Nile Virus Envelope (WNV E))

Alternative Name: West Nile Virus Envelope Protein

Target Type: Viral Protein