TSHB antibody

Catalog No. ABIN7794914

This Mouse Monoclonal antibody specifically detects TSHB . It exhibits reactivity toward Human.

Quick Overview for TSHB antibody (ABIN7794914)

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TSHB antibody is un-conjugated

Application: Please inquire

Clone: 183

Product Details anti-TSHB Antibody

Purpose: Anti-Human Thyroid Stimulating Hormone Beta (Clone 183)-Purified

Specificity: Mouse Anti-Human Thyroid Stimulating Hormone Beta (TSH-?) (Clone 183) recognizes Human Thyroid Stimulating Hormone Beta. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Thyroid-stimulating hormone (TSH), also known as thyrotropin, is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3

Immunogen: Purified Recombinant Human TSH-beta (>98%)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Concentration: 1 μg/mL

Buffer: This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: This purified antibody is stable when stored at 2-8°C. Do not freeze.

Target Details for TSHB

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Alternative Name: Thyroid Stimulating Hormone Beta

Background: HCG, GPH, GPHA1, CGA, Thyrotropin,

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism