Influenza Virus Nucleoprotein antibody (Influenza A Virus) (Biotin)
Quick Overview for Influenza Virus Nucleoprotein antibody (Influenza A Virus) (Biotin) (ABIN7794968)
Target
See all Influenza Virus Nucleoprotein (IV NP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Influenza A, Nucleocapsid (Clone 703) Biotin
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Specificity
- Anti-Influenza A, Nucleocapsid (Clone 703) specifically targets an epitope on the Influenza A Nucleocapsid Protein Antigen Distribution The nucleocapsid protein is expressed in the internal nucleocapsid of Influenza A Background There are four types of Influenza (flu) viruses type A, B, C, and D. Influenza A and B viruses are routinely spread in people and other mammals, while also known for seasonal flu epidemics each year. Influenza A is the genus Alphainfluenzavirus of the virus family Orthomyxoviridae. Influenza A is classified into two main protein subtypes, hemagglutinin (HA) and neuraminidase (NA), located on the surface of the virus. Breaking down the proteins further, there are 18 hemagglutinin subtypes and 11 different neuraminidase subtypes1. Influenza A can be even further classified into specific clades (also known as groups) and sub-clades (also known as sub-groups) based on similarity of their HA/NA gene sequences1. The Nucleocapsid protein or nucleoprotein (NP) of the influenza virus A negative-strand RNA?s primary function is to encapsulate the virus genome for the purpose of RNA transcription, replication and packaging2. Specifically, NP is the most abundant viral protein in infected cells2, therefore the NP can be and has been used for anti-influenza drug development3 The NP of influenza A and B viruses share up to 38 % of their amino acid sequence, indicating region functionality differences at the amino acid level4
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Isotype
- IgG1
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Restrictions
- For Research Use only
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Concentration
- 0.5 μg/mL
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Buffer
- This Biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1 % BSA and 0.09 % sodium azide as a preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
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- Influenza Virus Nucleoprotein (IV NP)
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Alternative Name
- Influenza A Nucleocapsid
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Target Type
- Influenza Protein
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Background
- Common flu NP, Influenza A virus NP, NP, Nucleocapsid protein, Nucleoprotein, Protein N, Seasonal Influenza A (H1N1) Nucleocapsid Protein,
Target
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