Recombinant IL-6R (Tocilizumab Biosimilar) antibody

Catalog No. ABIN7795095

The Humanized Monoclonal anti-IL-6R (Tocilizumab Biosimilar) antibody is suitable to detect IL-6R (Tocilizumab Biosimilar) in samples from Human. It has been validated for FACS and in vivo.

Quick Overview for Recombinant IL-6R (Tocilizumab Biosimilar) antibody (ABIN7795095)

Target: IL-6R (Tocilizumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Humanized

Clonality: Monoclonal

Conjugate: This IL-6R (Tocilizumab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Grade: Research Grade

Product Details anti-IL-6R (Tocilizumab Biosimilar) Antibody

Expression System: Mammalian cells

Purpose: Tocilizumab Biosimilar, Human IL-6R Monoclonal Antibody

Characteristics: What is tocilizumab biosimilar research grade? Tocilizumab biosimilar uses the same protein sequences as the therapeutic antibody tocilizumab. Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. Interleukin 6 (IL-6) is a pro-inflammatory cytokine produced by cells including T-cells, B-cells, lymphocytes, monocytes, fibroblasts. IL-6 rapidly induces C-reactive protein, serum amyloid A, fibrinogen, haptoglobin, and α-1-antichymotrypsin while inhibiting production of fibronectin, albumin, and transferrin. IL-6 also induces antibody production, induces cytotoxic T-cell differentiation, and inhibits regulatory T-cell differentiation. Tocilizumab binds soluble and membrane bound IL-6 receptors, preventing IL-6 mediated inflammation.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human IL-6R

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for IL-6R (Tocilizumab Biosimilar)

Target: IL-6R (Tocilizumab Biosimilar)

Alternative Name: Tocilizumab Biosimilar

Target Type: Biosimilar