Recombinant IL17A (Secukinumab Biosimilar) antibody
Quick Overview for Recombinant IL17A (Secukinumab Biosimilar) antibody (ABIN7795097)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
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Expression System
- Mammalian cells
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Purpose
- Secukinumab Biosimilar, Human IL17A Monoclonal Antibody
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Characteristics
- What is secukinumab biosimilar research grade? Research grade secukinumab biosimilar uses the same protein sequences as the therapeutic antibody secukinumab. Secukinumab, the humanized anti-IL17A monoclonal antibody, inhibits interleukin 17A, which is a member of the cytokine family, and produced mainly by inflammatory T helper 17 cells. IL17A is upregulated in serum of people with psoriasis and in the synovial fluid of people with psoriatic arthritis, and promotes inflammation when it binds to the interleukin-17 receptor which is expressed in various types of cells, including keratinocytes in skin.
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Endotoxin Level
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- Human IL17A
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- IL17A (Secukinumab Biosimilar)
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Alternative Name
- Secukinumab Biosimilar
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Target Type
- Biosimilar
Target
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