Recombinant IL12B (Briakinumab Biosimilar) antibody
Quick Overview for Recombinant IL12B (Briakinumab Biosimilar) antibody (ABIN7795102)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
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Expression System
- Mammalian cells
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Purpose
- Briakinumab Biosimilar, IL-12 / IL-23 Monoclonal Antibody
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Characteristics
- What is Briakinumab Biosimilar research grade? Briakinumab is a human anti-IL-12 / IL-23 monoclonal antibody being developed for the treatment of a number of T-cell driven autoimmune diseases. It targets and neutralize interleukin-12 and interleukin-23, two proteins associated with inflammation, such as pro-inflammatory interleukins or tumor necrosis factor- alpha. Briakinumab represents a novel approach to treating psoriasis, Multiple Sclerosis, Crohn's Disease and other autoimmune and inflammatory disorders. Briakinumab Biosimilar uses the same protein sequences as the therapeutic antibody briakinumab.
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Endotoxin Level
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- Human IL-12 / IL-23
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- IL12B (Briakinumab Biosimilar)
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Alternative Name
- Briakinumab Biosimilar
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Target Type
- Biosimilar
Target
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