Recombinant CD4 (Ibalizumab Biosimilar) antibody
Quick Overview for Recombinant CD4 (Ibalizumab Biosimilar) antibody (ABIN7795119)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
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Expression System
- Mammalian cells
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Purpose
- Ibalizumab Biosimilar, Human CD4 Monoclonal Antibody
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Characteristics
- What is ibalizumab biosimilar research grade? Ibalizumab Biosimilar uses the same protein sequences as the therapeutic antibody ibalizumab which is a non-immunosuppressive humanised monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits HIV from entering cells. It is a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4 cell. Post-attachment inhibitors are a subclass of HIV drugs called entry inhibitors.
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Endotoxin Level
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- Human CD4
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD4 (Ibalizumab Biosimilar)
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Alternative Name
- Ibalizumab Biosimilar
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Target Type
- Biosimilar
Target
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