Recombinant SARS-CoV-2 Spike (Casirivimab Biosimilar) antibody
Quick Overview for Recombinant SARS-CoV-2 Spike (Casirivimab Biosimilar) antibody (ABIN7795137)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
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Expression System
- Mammalian cells
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Purpose
- Casirivimab Biosimilar, SARS-CoV-2 Spike Monoclonal Antibody
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Characteristics
- What is casirivimab biosimilar research grade? Casirivimab is a human monoclonal antibody directed against the spike protein of SARS-CoV-2. Casirivimab is a human monoclonal antibody (IgG1κ isotype). Casirivimab biosimilar uses the same protein sequences as the therapeutic antibody casirivimab. Casirivimab/imdevimab is a combination medicine used for the treatment and prevention of COVID-19. It consists of two human monoclonal antibodies, casirivimab and imdevimab that must be mixed together and administered as an infusion or subcutaneous injection. The combination of two antibodies is intended to prevent mutational escape. Casirivimab and imdevimab bind distinct epitopes on the RBD with dissociation constants KD of 46 and 47 pM, respectively. Please contact us if you are interested in the anti-SARS-CoV-2 spike monoclonal antibody imdevimab biosimilar.
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Endotoxin Level
- < 1 EU per 1 mg of the protein by the LAL method
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Isotype
- IgG1, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- SARS-CoV-2 Spike (Casirivimab Biosimilar)
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Alternative Name
- Casirivimab Biosimilar
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Target Type
- Biosimilar
Target
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