Recombinant CD19 antibody
Quick Overview for Recombinant CD19 antibody (ABIN7795340)
Target
See all CD19 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Expression System
- Mammalian cells
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Purpose
- Recombinant Anti-human CD19 Monoclonal Antibody (Clone: SJ25C1), Mouse IgG1 Kappa
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Characteristics
- The SJ25C1 antibody binds to the human CD19 protein, a transmembrane protein expressed in all B lineage cells including human plasma cells. CD19 plays two major roles in human B cells: it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane, and works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. CD19 is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD19 (CD19 Molecule (CD19))
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Alternative Name
- CD19
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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