Recombinant CD3 epsilon antibody

Catalog No. ABIN7795360

The Mouse Monoclonal anti-CD3 epsilon antibody (Clone 12F6) (ABIN7795360) specifically detects CD3 epsilon in ELISA, Func, Neut and IGA. The antibody is reactive with Human samples.

Quick Overview for Recombinant CD3 epsilon antibody (ABIN7795360)

Target: CD3 epsilon (CD3E)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 epsilon antibody is un-conjugated

Application: ELISA, Functional Studies (Func), Neutralization (Neut), Immunogenicity Assay (IGA)

Grade: In vivo Grade

Clone: 12F6

Product Details anti-CD3 epsilon Antibody

Expression System: Mammalian cells

Purpose: In vivo Grade Recombinant Anti-human CD3e Monoclonal Antibody (Clone: 12F6), Mouse IgG2a Kappa

Characteristics: The 12F6 antibody competes with the OKT3 antibody for binding to human T cells, and has more effective T-cell suppression and activation properties than OKT3. The 12F6 antibody is used to study T-cell functions and to manipulate T-cell activation and suppression, prevent acute allograft rejection, and treat autoimmune diabetes.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for CD3 epsilon

Target: CD3 epsilon (CD3E)

Alternative Name: CD3e

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway