Recombinant CD3 epsilon antibody
Quick Overview for Recombinant CD3 epsilon antibody (ABIN7795400)
Target
See all CD3 epsilon (CD3E) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Expression System
- Mammalian cells
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Purpose
- Recombinant Anti-human CD3e Monoclonal Antibody (Clone: 12F6), Mouse IgG2a Kappa
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Characteristics
- The 12F6 antibody competes with the OKT3 antibody for binding to human T cells, and has more effective T-cell suppression and activation properties than OKT3. The 12F6 antibody is used to study T-cell functions and to manipulate T-cell activation and suppression, prevent acute allograft rejection, and treat autoimmune diabetes.
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Isotype
- IgG2a
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD3 epsilon (CD3E)
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Alternative Name
- CD3e
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Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Target
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