Recombinant CTLA4 antibody

Catalog No. ABIN7795498

The Human Monoclonal anti-CTLA4 antibody (Clone 9D9) (ABIN7795498) specifically detects CTLA4 in FACS. The antibody is reactive with Mouse samples.

Quick Overview for Recombinant CTLA4 antibody (ABIN7795498)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Human

Clonality: Monoclonal

Conjugate: This CTLA4 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 9D9

Product Details anti-CTLA4 Antibody

Expression System: Mammalian cells

Purpose: Recombinant Anti-mouse CTLA-4 Monoclonal Antibody (Clone: 9D9), Human IgG1 Fc Silent Kappa

Characteristics: The 9D9 antibody blocks the mouse cytotoxic T lymphocyte antigen-4 (CTLA-4). Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is an inhibitory molecule that competes with the stimulatory CD28 for binding to B7 on antigen presenting cells. CTLA-4 and CD28 are both presented on the surface of T-cells.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Isotype: Fc Silenced, IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Alternative Name: CTLA-4

Pathways: Cancer Immune Checkpoints