Recombinant TIGIT antibody

Catalog No. ABIN7795512

The Human Monoclonal anti-TIGIT antibody has been validated for FACS. It is suitable to detect TIGIT in samples from Mouse.

Quick Overview for Recombinant TIGIT antibody (ABIN7795512)

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Human

Clonality: Monoclonal

Conjugate: This TIGIT antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 1F4

Product Details anti-TIGIT Antibody

Expression System: Mammalian cells

Purpose: Recombinant Anti-mouse TIGIT Monoclonal Antibody (Clone: 1F4), Human IgG1 Fc Silent Kappa

Characteristics: The 1F4 antibody binds to the TIGIT protein (WUCAM, Vstm3 or VSIG9), a novel immune checkpoint receptor with inhibitory function. TIGIT is expressed on T cells and natural killer (NK) cells, and several human cancers, including melanoma, NSCLC, and colorectal cancer. Similar to PD-1, the TIGIT receptor limits antitumor immune response in cancer.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Isotype: Fc Silenced, IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Alternative Name: TIGIT

Pathways: Cancer Immune Checkpoints