Recombinant CD70 antibody (AA 50-193)

Catalog No. ABIN7795663

The Rabbit Monoclonal anti-CD70 antibody (Clone BLR266L) (ABIN7795663) specifically detects CD70 in WB, IHC and ICC. The antibody is reactive with Human samples.

Quick Overview for Recombinant CD70 antibody (AA 50-193) (ABIN7795663)

Target: CD70 (CD70 Molecule (CD70))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR266L

Product Details anti-CD70 Antibody

Binding Specificity: AA 50-193

Purpose: Rabbit anti-CD70 Recombinant Monoclonal Antibody [BLR266L]

Purification: Purified

Immunogen: Residues 50-193 (ECD)

Isotype: IgG

Application Details

Application Notes: ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background: CD70, a cytokine that belongs to the tumor necrosis factor (TNF) ligand family, is a ligand for TNFRSF27/CD27. CD70 is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. CD70 also plays a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. [taken from NCBI Entrez Gene (Gene ID: 970)].

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints