Recombinant YTHDF2 antibody (AA 300-350)

Catalog No. ABIN7795701

The Rabbit Monoclonal anti-YTHDF2 antibody has been validated for WB and FACS. It is suitable to detect YTHDF2 in samples from Human and Mouse.

Quick Overview for Recombinant YTHDF2 antibody (AA 300-350) (ABIN7795701)

Target: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This YTHDF2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: BLR297M

Product Details anti-YTHDF2 Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-YTHDF2 Recombinant Monoclonal Antibody [BLR297M]

Purification: Purified

Immunogen: Between 300 and 350

Isotype: IgG

Application Details

Application Notes: WB,11000,Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for YTHDF2

Target: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Alternative Name: YTHDF2

Background: YTHDF2 is a member of the YTH-domain containing (YT521-B homology) superfamily which also contains YTHDF1 and YTHDF3. These proteins share a conserved C-terminal YTH domain that specifically interacts with N6-methyladenosine (m6A) modified RNA. The m6A modification is present at internal sites of mRNAs and some non-coding RNAs and plays an important role in mRNA splicing, processing, and stability. YTHDF2 binding appears to promote mRNA degradation, but has minimal effect on translation efficiency. [adapted from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y5A9].

Gene ID: 51441

UniProt: Q9Y5A9