Recombinant IL-4 antibody (AA 25-153)

Catalog No. ABIN7795704

The Rabbit Monoclonal anti-IL-4 antibody has been validated for WB and IP. It is suitable to detect IL-4 in samples from Human.

Quick Overview for Recombinant IL-4 antibody (AA 25-153) (ABIN7795704)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL-4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: BLR298L

Product Details anti-IL-4 Antibody

Binding Specificity: AA 25-153

Purpose: Rabbit anti-IL-4 Recombinant Monoclonal Antibody [BLR298L] - BSA-Free

Purification: Purified

Immunogen: Residues 25-153

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4

Background: IL-4 is a pleiotropic cytokine produced by activated T cells. It acts by binding to the interleukin 4 receptor and STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. IL-4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation. In an allergic response, IL-4 has an essential role in the production of allergen-specific immunoglobin (Ig) E. [provided by RefSeq, Aug 2020] [taken from NCBI Entrez Gene (Gene ID: 3565)].

Gene ID: 3565

UniProt: P05112

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation