MEF2C
Reactivity: Human
IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11,000,IP,6 μL/mg lysate
Restrictions
For Research Use only
Format
Liquid
Concentration
1000 μg/mL
Buffer
Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
2 - 8 °C
Expiry Date
12 months
Target
MEF2C
(Myocyte Enhancer Factor 2C (MEF2C))
Alternative Name
MEF2C
Background
MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It also plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. MEF2C is crucial for normal neuronal development, distribution, and electrical activity in the neocortex. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q06413].