Recombinant IFI16 antibody (AA 350-400)

Catalog No. ABIN7795821

The Rabbit Monoclonal anti-IFI16 antibody has been validated for WB, IHC, IP and ICC. It is suitable to detect IFI16 in samples from Human.

Quick Overview for Recombinant IFI16 antibody (AA 350-400) (ABIN7795821)

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IFI16 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR375N

Product Details anti-IFI16 Antibody

Binding Specificity: AA 350-400

Purpose: Rabbit anti-IFI16 Recombinant Monoclonal Antibody [BLR375N]

Purification: Purified

Immunogen: between 350 and 400

Isotype: IgG

Application Details

Application Notes: WB,11000,IP,20 μL/mg lysate,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 250 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for IFI16

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Alternative Name: IFI16

Background: Gamma-interferon-inducible protein 16 (aka IFI16) is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. IFI16 contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions and localizes to the nucleoplasm and nucleoli. IFI16 interacts with p53 and retinoblastoma-1, modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. [taken from NCBI Entrez Gene (Gene ID: 3428)].

Gene ID: 3428

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome