TRF1 antibody (AA 121-220) (Cy5)

Catalog No. ABIN738415

This Rabbit Polyclonal antibody specifically detects TRF1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for TRF1 antibody (AA 121-220) (Cy5) (ABIN738415)

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF1 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TRF1 Antibody (Cy5)

Binding Specificity: AA 121-220

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TRBF1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Alternative Name: TRBF1/TRF1

Background:

Synonyms: hTRF1 AS, NIMA interacting protein 2, NIMA-interacting protein 2, PIN 2, PIN2, t TRF1, Telomeric protein Pin2, Telomeric protein Pin2/TRF1, Telomeric repeat binding factor NIMA interacting 1, Telomeric repeat binding factor 1, Telomeric repeat binding protein 1, Telomeric repeat-binding factor 1, TERF 1, TERF1, TERF1_HUMAN, TRBF 1, TRBF1, TRF 1, TRF, TTAGGG repeat binding factor 1, TTAGGG repeat-binding factor 1.

Background: This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq].

Gene ID: 7013

Pathways: Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity