CCR4 antibody (AA 201-300) (HRP)

Catalog No. ABIN738675

The HRP-conjugated Rabbit Polyclonal anti-CCR4 antibody (ABIN738675) specifically detects CCR4 in IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for CCR4 antibody (AA 201-300) (HRP) (ABIN738675)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CCR4 Antibody (HRP)

Binding Specificity: AA 201-300

Purpose: CCR4 Polyclonal Antibody, HRP Conjugated

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCR-4

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CCR4

Background:

Synonyms: CKR4, K5-5, CD194, CMKBR4, ChemR13, CC-CKR-4, HGCN:14099, C-C chemokine receptor type 4, C-C CKR-4, CCR-4, CCR4

Background: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Gene ID: 1233

UniProt: P51679