Arc antibody (AA 101-200)

Catalog No. ABIN739460

The Rabbit Polyclonal anti-Arc antibody has been validated for WB, ELISA and FACS. It is suitable to detect Arc in samples from Human, Rat and Mouse. There is 1 publication available.

Quick Overview for Arc antibody (AA 101-200) (ABIN739460)

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arc antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-Arc Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARC

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Arc antibody (ABIN739460)

Atluri, Kanthikeel, Reddy, Yndart, Nair: "Human synaptic plasticity gene expression profile and dendritic spine density changes in HIV-infected human CNS cells: role in HIV-associated neurocognitive disorders (HAND)." in: PLoS ONE, Vol. 8, Issue 4, pp. e61399, (2013) (PubMed).

Target Details for Arc

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Alternative Name: ARC/Arg3.1

Background:

Synonyms: Arg3.1, Activity-regulated cytoskeleton-associated protein, ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, ARC, KIAA278

Background: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.

Gene ID: 23237

UniProt: Q7LC44