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MDC1 antibody (AA 31-130) (Cy5)

This Rabbit Polyclonal antibody specifically detects MDC1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Catalog No. ABIN739744

Quick Overview for MDC1 antibody (AA 31-130) (Cy5) (ABIN739744)

Target

See all MDC1 Antibodies

MDC1 (Mdc1 (MDC1))

Reactivity

59
43
15
12
11
2
1
1

Human, Mouse, Rat

Host

Rabbit

Clonality

Polyclonal

Conjugate

29
6
6
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This MDC1 antibody is conjugated to Cy5

Application

57
22
14
13
12
12
12
10
9
6
3
2
1
1
1

Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Discover our top product MDC1 Primary Antibody

Binding Specificity
21

14

10

8

5

3

2

2

2

1

1

1

1

1

1

1

1

1
AA 31-130

Cross-Reactivity

Human, Mouse, Rat

Predicted Reactivity

Dog,Cow,Pig,Horse

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human MDC1

Isotype

IgG
anti-Mdc1 (MDC1) (AA 1-100) antibody
MDC1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Mdc1 (MDC1) antibody
MDC1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 1-350) antibody
MDC1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 31-130) antibody
MDC1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody (HRP)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 HRP

anti-Mdc1 (MDC1) (N-Term) antibody (FITC)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 FITC

anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 Biotin

anti-Mdc1 (MDC1) (N-Term) antibody (PE)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 PE

anti-Mdc1 (MDC1) (N-Term) antibody (APC)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 APC

Application Notes

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date

12 months
Target

MDC1 (Mdc1 (MDC1))

Alternative Name

Mdc1

Background

Synonyms: NFBD1, Mediator of DNA damage checkpoint protein 1, Nuclear factor with BRCT domains 1, MDC1, KIAA0170
Background: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.

Gene ID

9656

UniProt

Q14676

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