AKR1B1 antibody (AA 151-250) (Cy7)

Catalog No. ABIN739791

The Cy7-conjugated Rabbit Polyclonal anti-AKR1B1 antibody (ABIN739791) specifically detects AKR1B1 in WB, IF (cc) and IF (p). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for AKR1B1 antibody (AA 151-250) (Cy7) (ABIN739791)

Target: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1B1 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-AKR1B1 Antibody (Cy7)

Binding Specificity: AA 151-250

Specificity: This antibody may have a secondary cross-reactivity with AKR1C1/2/3/4 due to a 75 % sequence similarity in the corresponding immunogen regions.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKR1B1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AKR1B1

Target: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Alternative Name: Akr1b1

Background:

Synonyms: AR, ADR, ALR2, ALDR1, Aldose reductase, Aldehyde reductase, Aldo-keto reductase family 1 member B1, AKR1B1

Background: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

Gene ID: 231

UniProt: P15121

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process