SHANK3 antibody (AA 538-626) (FL550)

Catalog No. ABIN7823785

This Mouse Monoclonal antibody specifically detects SHANK3 in IHC and ICC. It exhibits reactivity toward Rat.

Quick Overview for SHANK3 antibody (AA 538-626) (FL550) (ABIN7823785)

Target: SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SHANK3 antibody is conjugated to FL550

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N367-62

Product Details anti-SHANK3 Antibody (FL550)

Binding Specificity: AA 538-626

Purpose: Anti-Shank3 Antibody FL550 Conjugate

Specificity: No off-targets reported for Shank1 or Shank2

Cross-Reactivity: Mouse

Characteristics: Our Anti-Shank3 mouse monoclonal primary antibody is produced in-house from hybridoma clone N367/62. It detects mouse and rat Shank3, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 538-626 (SH3 domain) of rat Shank3 (accession number Q9JLU4) produced recombinantly in E. Coli

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for SHANK3

Target: SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))

Alternative Name: Shank3

Background:

Synonyms: SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)

Description Logic: Our Anti-Shank3 mouse monoclonal primary antibody is produced from hybridoma clone N367/62. It detects mouse and rat Shank3, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: Shank3 Prosap2

Molecular Weight: 190 kDa

UniProt: Q9JLU4

Pathways: Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity