SPTBN1 antibody (C-Term) (FL490)

Catalog No. ABIN7823869

This Mouse Monoclonal antibody specifically detects SPTBN1 in IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for SPTBN1 antibody (C-Term) (FL490) (ABIN7823869)

Target: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPTBN1 antibody is conjugated to FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N385-21

Product Details anti-SPTBN1 Antibody (FL490)

Binding Specificity: AA 1555-2137, C-Term

Purpose: Anti-Beta1-Spectrin Antibody FL490 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Mouse, Rat

Characteristics: Our Anti-Beta1-spectrin mouse monoclonal primary antibody is produced in-house from hybridoma clone N385/21. It detects human, mouse, and rat Beta1-spectrin, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 1555-2137 (C-terminal repeats 13 to 17) of human Beta1-spectrin (accession number P11277) produced recombinantly in E. Coli

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for SPTBN1

Target: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Alternative Name: Beta1-spectrin

Background:

Synonyms: Spectrin beta chain, erythrocytic (Beta-I spectrin)

Description Logic: Our Anti-Beta1-spectrin mouse monoclonal primary antibody is produced from hybridoma clone N385/21. It detects human, mouse, and rat Beta1-spectrin, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: SPTB SPTB1

Molecular Weight: 250 kDa

UniProt: P11277

Pathways: Regulation of Actin Filament Polymerization, Protein targeting to Nucleus