NOS1 antibody (AA 350-720) (FL594)

Catalog No. ABIN7824311

The Mouse Monoclonal anti-NOS1 antibody has been validated for IHC and ICC. It is suitable to detect NOS1 in samples from Human.

Quick Overview for NOS1 antibody (AA 350-720) (FL594) (ABIN7824311)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NOS1 antibody is conjugated to FL594

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: L121-25

Product Details anti-NOS1 Antibody (FL594)

Binding Specificity: AA 350-720

Purpose: Anti-nNOS/NOS1 Antibody FL594 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Mouse, Rat

Characteristics: Our Anti-nNOS/NOS1 mouse monoclonal primary antibody is produced in-house from hybridoma clone L121/25. It detects human, mouse, and rat nNOS/NOS1, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 350-720 of human NOS1 (accession number P29475) produced recombinantly in E. Coli

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Alternative Name: nNOS/NOS1

Background:

Synonyms: NOS1 (Brain nitric oxide synthase) (Constitutive NOS) (Neuronal NOS) (Peptidyl-cysteine S-nitrosylase NOS1)

Description Logic: Our Anti-nNOS/NOS1 mouse monoclonal primary antibody is produced from hybridoma clone L121/25. It detects human, mouse, and rat nNOS/NOS1, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: NOS1

Molecular Weight: 155-165 kDa for full-length protein, smaller fragments possible due to proteolysis and/or variable sample preparation

UniProt: P29475

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction